NIPT: give parents the full story
Writing in response to an article on NIPT in last month's issue of
I was delighted to read the article (Lancaster, 2019) in British Journal of Midwifery (BJM), discussing the importance of continuing the conversation around prenatal screening and, in particular, non-invasive prenatal testing (NIPT).
One of the many issues with NIPT is that some of the ways it has been described during commercial marketing are misleading to consumers and professionals. The concern is that women may then make decisions informed by the ‘popular’ view of what NIPT is, rather than the factual. Some of these misleading statements are quite subtle but important.
The DNA analysed is a mixture of the mother's DNA and the DNA from the placenta. This is not DNA from the fetus and is one of the reasons that the test may be wrong, due to placental mosaicism. Describing the DNA as ‘fetal’ or ‘from the fetus’ is at best misleading and at worst incorrect, as barely any DNA passes from the fetus through the placenta—certainly not enough to give results for NIPT. It also gives the impression that it is the baby's DNA being directly analysed, which may, in women's minds, imply greater accuracy than is possible with NIPT.
Register now to continue reading
Thank you for visiting British Journal of Midwifery and reading some of our peer-reviewed resources for midwives. To read more, please register today. You’ll enjoy the following great benefits:
Limited access to our clinical or professional articles
Unlimited access to the latest news, blogs and video content
Monthly email newsletter